AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Dynamic light scattering protein2/1/2024 ![]() This is the main cookie set by Hubspot, for tracking visitors. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. The pll _language cookie is used by Polylang to remember the language selected by the user when returning to the website, and also to get the language information when not available in another way.Īnalytical cookies are used to understand how visitors interact with the website. LinkedIn sets the lidc cookie to facilitate data center selection. This cookie is used to store the language preferences of a user to serve up content in that stored language the next time user visit the website. LinkedIn sets this cookie from LinkedIn share buttons and ad tags to recognize browser ID. HubSpot sets this cookie to keep track of sessions and to determine if HubSpot should increment the session number and timestamps in the _hstc cookie. This cookie, set by Cloudflare, is used to support Cloudflare Bot Management. It does not store any personal data.įunctional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The cookie is used to store the user consent for the cookies in the category "Performance". This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. ![]() The cookies is used to store the user consent for the cookies in the category "Necessary". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The cookie is used to store the user consent for the cookies in the category "Analytics". The _hssrc cookie set to 1 indicates that the user has restarted the browser, and if the cookie does not exist, it is assumed to be a new session. This cookie is set by Hubspot whenever it changes the session cookie. These cookies ensure basic functionalities and security features of the website, anonymously. Necessary cookies are absolutely essential for the website to function properly. Aggregation is indicated by peaks to the right of those observed in the buffer blank. ![]() Dynamic Light Scatteringįigure A: DLS data for a compound at aggregating and sub-aggregating concentrations, illustrating the raw correlation functions (left) and the corresponding intensity distribution (right). The correlation between time points is used to determine the radii of nanometre-scale objects in solution. Preformulation and Formulation Developmentĭynamic light scattering (DLS) is a Biophysical Technique that enables particles to be distinguished on the basis of their size. Sygnature have experience in the utilisation of this technique using the Viscotek DLS reader, to interrogate the stoichiometry of protein-protein interactions and to identify aggregating compounds or non-specific inhibitors, adding value to our client’s discovery programs via hit validation, protein characterisation and assay troubleshooting.ĭLS enables an assessment of compound, protein or protein-ligand binding complex aggregation behaviour by measuring the correlation between the intensity of scattered light over a time course.Metabolite Drug Identification (Met-ID).Fluorescent Thermal Shift Assays (FTSA).Cellular interaction and Co-Culture Assay Systems.
0 Comments
Read More
Leave a Reply. |